T087. Clinical Significance and Detection of Carbapenemases and other Newer ß-Lactamases
Originally Presented: October 21, 2009
Speaker: Kenneth S. Thompson

Summary of Session: The primary focus will be on the laboratory detection and clinical significance of carbapenemases. Some issues concerning extended spectrum ß-lactamases and plasmid-mediated AmpC ß-lactamases will also be addressed. These enzymes cause therapeutic, infection control, and diagnostic problems.

Objectives: Upon completion of this Teleconference, participants should be able to:

• Explain the concerns about carbapenemases, extended spectrum ß-lactamases (ESBLs), and plasmid-mediated AmpC ß-lactamases;
• Identify gaps in CLSI recommendations to detect these enzymes;
• Recognize that detection of carbapenemases is an important challenge facing clinical laboratories; and
• Discuss laboratory tests that may be useful to screen and confirm isolates for production of these enzymes.

Intended Audience: Clinical microbiology laboratory and infection control personnel.

CME Disclosures: The Presenter has nothing to disclose.

Termination of CME Credit: This program will not be eligible for CME credit after October 21, 2010